Leaving behind her 1950s advertising career as a Madison Avenue illustrator, Seigel evolved from painting surrealistic landscapes to abstract “organic chemistry” in acrylic on large canvasses in the 1960s- 1970s. Her “secret process” of washes, scraping, squeeze bottling, and pattern overlays, she wrote, was inspired by printmaking, experimental photography, computer graphics, TV test patterns and airwave broadcast interference. Reviewers likened her Channel Six series to “infrared aerial photography” (“Visual Dialogues,” 1976/1977) that emit “the light energy of ionized atoms” (WomanArt, 1977).